Residues of gentamicin in eggs following medication of laying hens

Br Poult Sci. 2005 Oct;46(5):580-3. doi: 10.1080/00071660500273243.

Abstract

1. Gentamicin was injected subcutaneously and intramuscularly into 5 groups of 10 laying hens and its concentration was determined in albumen, yolk and whole egg. 2. Groups 1 and 3 were intramuscularly injected with doses of 10 and 25 mg/kg while groups 2, 4 and 5 were subcutaneously injected with doses of 10, 25 and 50 mg/kg, respectively. 3. The final gentamicin concentration in albumen was measured on d 3 for groups 1 and 2; on d 4 for groups 3 and 4, and on d 5 for group 5. Concentrations in yolk and whole egg were measured on d 7, 10 and 12. 4. Gentamicin recovery was as follows: 2% in groups 1 and 2, 2.5% in groups 3 and 4, and 3% in group 5. 5. Most of the residue (approximately 90%) was recovered from the yolk.

Publication types

  • Clinical Trial
  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / analysis
  • Anti-Bacterial Agents / pharmacokinetics
  • Anti-Bacterial Agents / therapeutic use
  • Chickens*
  • Dose-Response Relationship, Drug
  • Drug Residues / analysis*
  • Female
  • Gentamicins / administration & dosage
  • Gentamicins / analysis*
  • Gentamicins / pharmacokinetics
  • Gentamicins / therapeutic use*
  • Injections, Intramuscular
  • Injections, Subcutaneous
  • Ovum / chemistry*
  • Time Factors

Substances

  • Anti-Bacterial Agents
  • Gentamicins