Effects of cytomegalovirus (CMV) related deafness on pediatric cochlear implant outcomes

Otolaryngol Head Neck Surg. 2005 Dec;133(6):900-5. doi: 10.1016/j.otohns.2005.08.013.

Abstract

Objective: Human cytomegalovirus (CMV) is a commonly recognized viral cause of perinatal sensorineural hearing loss. CMV-infected infants are also at risk for developmental neurological deficits. This retrospective study assesses the impact of CMV-induced deafness on pediatric cochlear implant outcomes.

Study design and setting: Thirteen patients from the Johns Hopkins pediatric cochlear implant database were identified with CMV-related deafness. A retrospective review of the medical records of the Johns Hopkins Hospital was performed.

Results: The mean age at implantation was 5.6 years. Follow-up audiometric data ranged from 6 to 48 months postoperatively. Mean speech perception scores were 4.5 (out of 6) following implantation.

Conclusion: We have shown that cochlear implants can provide useful speech comprehension to patients with CMV-related deafness. Speech recognition scores were within the range established by our overall pediatric implant population.

Significance: This observation underscores the importance of a multidisciplinary rehabilitation program following implantation in these patients at risk for cognitive delay.

Publication types

  • Comparative Study

MeSH terms

  • Antibodies, Viral / immunology
  • Child
  • Child, Preschool
  • Cochlear Implantation / instrumentation*
  • Cochlear Implants*
  • Cytomegalovirus / immunology
  • Cytomegalovirus Infections / complications*
  • Cytomegalovirus Infections / virology
  • Deafness / etiology*
  • Deafness / physiopathology
  • Deafness / surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Male
  • Retrospective Studies
  • Speech Perception / physiology
  • Speech Reception Threshold Test
  • Treatment Outcome

Substances

  • Antibodies, Viral