Circadian pathway: the other shoe drops

Curr Biol. 2005 Dec 20;15(24):R987-9. doi: 10.1016/j.cub.2005.11.053.

Abstract

Three new papers report the long-awaited functional characterization of the Drosophila receptor for the circadian-rhythm-regulating signalling molecule PIGMENT DISPERSING FACTOR (PDF). The discovery of the PDF receptor heralds progress in understanding the circadian pacemaker circuit and output pathways in insects.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Communication / genetics
  • Cell Communication / physiology
  • Circadian Rhythm / genetics*
  • Circadian Rhythm / physiology
  • Drosophila / genetics*
  • Drosophila / physiology
  • Drosophila Proteins / genetics*
  • Drosophila Proteins / metabolism
  • Neurons / metabolism*
  • Neuropeptides / genetics*
  • Neuropeptides / metabolism
  • Receptors, G-Protein-Coupled / genetics*
  • Receptors, G-Protein-Coupled / metabolism

Substances

  • Drosophila Proteins
  • Neuropeptides
  • PDFR protein, Drosophila
  • Receptors, G-Protein-Coupled
  • pdf protein, Drosophila