Intracellular protein degradation and its therapeutic implications

Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8530-3. doi: 10.1158/1078-0432.CCR-05-2305.

Authors

Teru Hideshima¹, James E Bradner, Dharminder Chauhan, Kenneth C Anderson

Affiliation

¹ Jerome Lipper Multiple Myeloma Center, Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts 02115, USA.

PMID: 16361533
DOI: 10.1158/1078-0432.CCR-05-2305

No abstract available

Publication types

Review

MeSH terms

Humans
Lysosomes / metabolism*
Multiple Myeloma / drug therapy*
Multiple Myeloma / metabolism
Proteasome Inhibitors*
Proteins / metabolism*

Substances

Proteasome Inhibitors
Proteins