Fine needle aspiration cytology of silicone lymphadenopathy in a patient with an artificial joint. A case report

Acta Cytol. 1992 Jul-Aug;36(4):529-32.


Three years after replacement of the left first metatarsophalangeal joint with a silicone prosthesis, a patient noted enlargement of a left femoral lymph node. Fine needle aspiration of the node revealed a foreign body giant cell reaction to particulates morphologically compatible with silicone elastomer. This finding suggests the potential utility of fine needle aspiration in the evaluation of patients' responses to a variety of foreign materials used in prosthetic devices and as pharmaceuticals.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Female
  • Humans
  • Joint Prosthesis / adverse effects*
  • Lymphatic Diseases / etiology*
  • Lymphatic Diseases / pathology
  • Middle Aged
  • Silicone Elastomers / adverse effects*


  • Silicone Elastomers