Neurobehavioral functioning in a nonconfounded group of asymptomatic HIV-seropositive homosexual men

Am J Psychiatry. 1992 Aug;149(8):1099-102. doi: 10.1176/ajp.149.8.1099.


Neurobehavioral functioning was tested in 34 asymptomatic HIV-seropositive and 43 HIV-seronegative male homosexual subjects without substance abuse and CNS disorders. The HIV-positive subjects exhibited mild motor slowing compared to the seronegative subjects. These differences remained after controlling for potential cofactors. Early neurobehavioral impairment in HIV infection seems limited to subclinical motor deficits and attributable to HIV rather than possible confounding factors.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Depressive Disorder / complications
  • Depressive Disorder / diagnosis
  • HIV Seropositivity / complications
  • HIV Seropositivity / diagnosis*
  • Homosexuality*
  • Humans
  • Male
  • Middle Aged
  • Motor Skills
  • Neuropsychological Tests* / statistics & numerical data
  • Psychiatric Status Rating Scales
  • Psychomotor Performance