Self-injection of monthly combined hormonal contraceptive

Contraception. 2006 Jan;73(1):53-5. doi: 10.1016/j.contraception.2005.05.020. Epub 2005 Nov 14.


Objectives: The monthly injectable contraceptive is usually administered in the office. We aimed to compare home self-injection with office administration with respect to satisfaction, compliance, and time and money spent on contraceptive behavior.

Methods: We enrolled 16 subjects and taught them self-injection for a prospective cohort trial with crossover. Subjects performed three self-injections at home and then had three office injections by the nurse.

Results: Ten subjects completed the protocol. They reported similarly low pain and anxiety with nurse injections and self-injections. Women reported spending less money and similar time for home injections. Most subjects strongly preferred giving themselves injections at home to office injections and would recommend self-injection to other women.

Conclusions: Self-injection of the monthly contraceptive at home is a preferable alternative to office administration for these subjects. This study demonstrates the feasibility of teaching women self-injection. Future studies should look at how best to teach women self-injection and to select women who will be successful with self-injection of contraceptives.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Cohort Studies
  • Contraceptives, Oral, Combined / administration & dosage*
  • Contraceptives, Oral, Combined / economics
  • Cross-Over Studies
  • Female
  • Humans
  • Injections, Intramuscular
  • Patient Education as Topic
  • Patient Satisfaction
  • Prospective Studies
  • Self Administration* / economics


  • Contraceptives, Oral, Combined