Corneal injury by anti-misting agent in swim goggles: a case report

Cornea. 2006 Feb;25(2):228-31. doi: 10.1097/01.ico.0000176613.73332.96.


Purpose: To report a case of corneal injury by swim goggle anti-misting agent.

Methods: Case report.

Results: A 47-year-old man presented with ocular injury caused by swim goggle anti-misting agent. Two weeks previously, the patient felt sudden ocular pain and grit after pool water flooded his goggles while swimming. Before the patient's swim, a copious amount of anti-misting agent was sprayed inside his goggles. On examination, severe corneal epithelial defect and stroma edema of the right eye were noted. Best-corrected visual acuity (BCVA) was 20/40. Right eye corneal thickness was 625 microm. Topical corticosteroids, antibiotic eye drops, and oral tetracycline were started. After 1 week of treatment, the epithelial defect of his right cornea improved slightly. Stromal edema decreased mildly. Epithelial defect persisted at 1 month follow-up. Right eye BCVA remained 20/40. Three months after treatment, the right eye epithelial defect healed completely. Mild diffuse superficial stromal opacity was noted. BCVA improved to 20/20. At 1-year follow-up, right eye corneal thickness was 547 microm, which was thinner than the left eye. Right eye corneal endothelial cell density measured approximately 1500 cells/mm2, which was less than the left eye at 2300 cells/mm2. The faint, diffuse stromal opacity disappeared; however, white subepithelial plaques were noted in the cornea centers. After 1 month of treatment with topical corticosteroids, the plaques subsided completely. The corneas remained clear at 2-year follow-up.

Conclusion: Anti-misting agent can cause severe corneal injuries, including persistent epithelial defects, stromal edema and opacity, endothelial cell loss, and subepithelial plaque.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Burns, Chemical / drug therapy
  • Burns, Chemical / etiology*
  • Burns, Chemical / pathology
  • Cornea / pathology
  • Corneal Injuries*
  • Drug Combinations
  • Ethanol / adverse effects
  • Eye Burns / chemically induced*
  • Eye Burns / drug therapy
  • Eye Burns / pathology
  • Eye Protective Devices*
  • Follow-Up Studies
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / therapeutic use
  • Humans
  • Male
  • Methanol / adverse effects
  • Middle Aged
  • Ophthalmic Solutions
  • Surface-Active Agents / adverse effects*


  • Anti-Bacterial Agents
  • Drug Combinations
  • Glucocorticoids
  • Ophthalmic Solutions
  • Surface-Active Agents
  • Ethanol
  • Methanol