Bilateral infectious ulcers associated with atopic keratoconjunctivitis

Cornea. 2006 Feb;25(2):248-50. doi: 10.1097/01.ico.0000176606.79753.89.


Purpose: A case of atopic keratoconjunctivitis complicated by bilateral infectious ulcers is described.

Methods: Both eyes underwent complete ophthalmologic examination and in vivo confocal microscopy imaging by using the Heidelberg Retina Tomograph II Rostock-cornea-module (HRT II-RCM) and were photographed.

Results: Topical antibiotics and corticosteroids associated with oral antibiotics and corticosteroids were given. After 4 weeks of treatment, the corneal lesions healed completely.

Conclusion: Bilateral infectious ulcers with perforation are a rare and severe complication of atopic keratoconjunctivitis. HRT II-RCM in vivo confocal microscopy imaging is useful in monitoring the progression of ocular surface diseases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Conjunctivitis, Allergic / complications*
  • Corneal Ulcer / drug therapy
  • Corneal Ulcer / etiology*
  • Corneal Ulcer / pathology
  • Diagnosis, Differential
  • Drug Administration Routes
  • Follow-Up Studies
  • Functional Laterality
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / therapeutic use
  • Humans
  • Male
  • Microscopy, Confocal
  • Middle Aged


  • Anti-Bacterial Agents
  • Glucocorticoids