Hong Kong case-control study of sudden unexpected infant death

N Z Med J. 2005 Dec 16;118(1227):U1788.


Aim: To document causes of all unexpected child deaths under 2 years of age during a 4-year period (1999-2003), and to identify factors associated with sudden infant death syndrome (SIDS) in Hong Kong.

Methods: The case-control component of the study compared information from SIDS deaths (n=16) with healthy controls (n=223) identified randomly from all births in Hong Kong. Coroner records of all deaths under 2 years of age were later reviewed.

Results: SIDS risk factors included prone sleep position, smoking by mother, bedsharing with someone other than the parents, and baby found with head covered. Eighteen deaths were officially classified as SIDS but, on review of the coroner records, there were 33 potential SIDS deaths (many labelled as unascertained/unknown).

Conclusion: Hong Kong SIDS incidence has fallen from 0.3/1000 (95% CI: 0.18-0.46 in 1987) to 0.16/1000 (95% CI: 0.11-0.22 in 1999-2002). Despite the small number of cases, key SIDS risk factors are shown to be important in this population. Hong Kong needs to take steps to standardise the investigation and management of these deaths and to establish a child mortality review mechanism to provide feedback to the public, to the health authorities, and to health professionals.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Distribution
  • Birth Weight
  • Case-Control Studies
  • Child, Preschool
  • Female
  • Gestational Age
  • Hong Kong / epidemiology
  • Humans
  • Incidence
  • Infant
  • Logistic Models
  • Male
  • Parents
  • Pneumonia / mortality
  • Posture
  • Retrospective Studies
  • Risk Factors
  • Sleep
  • Socioeconomic Factors
  • Sudden Infant Death / epidemiology*
  • Tobacco Smoke Pollution / statistics & numerical data


  • Tobacco Smoke Pollution