Retinopathy in persons with impaired glucose metabolism: the Australian Diabetes Obesity and Lifestyle (AusDiab) study

Am J Ophthalmol. 2005 Dec;140(6):1157-9. doi: 10.1016/j.ajo.2005.07.030.


Purpose: To describe risk factors and vascular disease associations of retinopathy in people with impaired glucose metabolism.

Design: Population-based cross-sectional study.

Methods: Retinal photographs taken of participants with impaired glucose tolerance and impaired fasting glucose were graded for retinopathy. Risk factors and cardiovascular outcomes were ascertained.

Results: Retinopathy was present in 69 (6.7%) of 1027 participants with impaired glucose tolerance or impaired fasting glucose. After multivariate adjustment, retinopathy was associated with prevalent stroke (odds ratio 4.2, 95% confidence interval, 1.8 to 9.7).

Conclusions: Retinopathy is common in persons with impaired glucose metabolism and may be associated with prevalent stroke.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Australia
  • Blood Glucose / metabolism*
  • Cross-Sectional Studies
  • Diabetes Complications
  • Female
  • Glucose / metabolism*
  • Glucose Intolerance / blood
  • Glucose Intolerance / complications*
  • Glucose Tolerance Test
  • Humans
  • Life Style
  • Male
  • Middle Aged
  • Obesity / complications
  • Retinal Diseases / blood
  • Retinal Diseases / complications*
  • Risk Factors
  • Stroke / blood
  • Stroke / complications*


  • Blood Glucose
  • Glucose