Sex differentiation: the role of alternative splicing

Curr Opin Genet Dev. 1992 Apr;2(2):299-303. doi: 10.1016/s0959-437x(05)80288-6.


Sex differentiation in Drosophila is controlled by a regulatory cascade with at least three regulated alternative RNA-processing events. The results of recent work have verified much of the earlier molecular and genetic work in this field and have provided a demonstration that both positive and negative regulatory mechanisms are involved.

Publication types

  • Review

MeSH terms

  • Animals
  • Base Sequence
  • Drosophila / embryology*
  • Drosophila / genetics
  • Genes, Regulator / physiology*
  • Molecular Sequence Data
  • RNA Splicing / physiology*
  • Sex Differentiation / genetics