Pfam: clans, web tools and services

Nucleic Acids Res. 2006 Jan 1;34(Database issue):D247-51. doi: 10.1093/nar/gkj149.


Pfam is a database of protein families that currently contains 7973 entries (release 18.0). A recent development in Pfam has enabled the grouping of related families into clans. Pfam clans are described in detail, together with the new associated web pages. Improvements to the range of Pfam web tools and the first set of Pfam web services that allow programmatic access to the database and associated tools are also presented. Pfam is available on the web in the UK (, the USA (, France ( and Sweden (

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computer Graphics
  • Databases, Protein*
  • Internet
  • Markov Chains
  • Protein Structure, Tertiary
  • Proteins / chemistry
  • Proteins / classification*
  • Sequence Alignment
  • Software
  • User-Computer Interface


  • Proteins