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. 2006 Jan 1;34(Database issue):D267-9.
doi: 10.1093/nar/gkj104.

LGICdb: A Manually Curated Sequence Database After the Genomes

Free PMC article

LGICdb: A Manually Curated Sequence Database After the Genomes

Marco Donizelli et al. Nucleic Acids Res. .
Free PMC article


Ligand-gated ion channels form transmembrane ionic pores controlled by the binding of chemicals. The LGICdb aims to be a non-redundant, manually curated resource offering access to the large number of subunits composing extracellularly activated ligand-gated ion channels, such as nicotinic, ATP, GABA and glutamate ionotropic receptors. Composed of more than 500 human curated entries, the XML native database has been relocated in 2004 to the EBI. Its facilities have been enhanced with a new search system, customized multiple sequence alignments and manipulation of protein structures ( Despite the vast improvement of general sequence resources, the LGICdb still provide sequences unavailable elsewhere.


Figure 1
Figure 1
Schema describing the relationships between the various components of the LGICdb. Square boxes represent servers. http: Apache Hypertext Transfer Protocol server; jsp: Jakarta Tomcat Java Server Page. Gears represent external applications.

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