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, 34 (Database issue), D432-5

Genolevures Complete Genomes Provide Data and Tools for Comparative Genomics of Hemiascomycetous Yeasts


Genolevures Complete Genomes Provide Data and Tools for Comparative Genomics of Hemiascomycetous Yeasts

David Sherman et al. Nucleic Acids Res.


The Génolevures online database ( provides tools and data relative to 4 complete and 10 partial genome sequences determined and manually annotated by the Génolevures Consortium, to facilitate comparative genomic studies of hemiascomycetous yeasts. With their relatively small and compact genomes, yeasts offer a unique opportunity for exploring eukaryotic genome evolution. The new version of the Génolevures database provides truly complete (subtelomere to subtelomere) chromosome sequences, 25 000 protein-coding and tRNA genes, and in silico analyses for each gene element. A new feature of the database is a novel collection of conserved multi-species protein families and their mapping to metabolic pathways, coupled with an advanced search feature. Data are presented with a focus on relations between genes and genomes: conservation of genes and gene families, speciation, chromosomal reorganization and synteny. The Génolevures site includes an area for specific studies by members of its international community.


Figure 1
Figure 1
Links between Génolevures data and tools showing the principal workflows used by scientific users. Dark gray boxes represent dynamic, database-backed web pages, white boxes represent static web pages. Shorthand URL prefixes for these pages are shown in a monospaced font.

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    1. Kurtzmann C.P., Fell J.W., editors. The Yeasts, A Taxonomic Study, 4th edition. Amsterdam: Elsevier; 1998.
    1. Tawfik O.W., Papasian C.J., Dixon A.Y., Potter L.M. Saccharomyces cerevisiae pneumonia in a patient with acquired immune deficiency syndrome. J. Clin. Microbiol. 1989;27:1689–1691. - PMC - PubMed
    1. Goffeau A., Barrell B.G., Bussey H., Davis R.W., Dujon B., Feldmann H., Galibert F., Hoheisel J.D., Jacq C., Johnston M., et al. Life with 6000 genes. Science. 1996;274:546. 563–567. - PubMed
    1. Souciet J., Aigle M., Artiguenave F., Blandin G., Bolotin-Fukuhara M., Bon E., Brottier P., Casaregola S., de Montigny J., Duchateau-Nguyen G., et al. Génolevures: Genomic exploration of the hemiascomycetous yeasts. FEBS Lett. 2000;487:1–149. - PubMed
    1. Cliften P., Sudarsanam P., Desikan A., Fulton L., Fulton B., Majors J., Waterston R., Cohen B.A., Johnston M. Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science. 2003;301:71–76. - PubMed

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