WormBase: better software, richer content

Nucleic Acids Res. 2006 Jan 1;34(Database issue):D475-8. doi: 10.1093/nar/gkj061.


WormBase (http://wormbase.org), the public database for genomics and biology of Caenorhabditis elegans, has been restructured for stronger performance and expanded for richer biological content. Performance was improved by accelerating the loading of central data pages such as the omnibus Gene page, by rationalizing internal data structures and software for greater portability, and by making the Genome Browser highly customizable in how it views and exports genomic subsequences. Arbitrarily complex, user-specified queries are now possible through Textpresso (for all available literature) and through WormMart (for most genomic data). Biological content was enriched by reconciling all available cDNA and expressed sequence tag data with gene predictions, clarifying single nucleotide polymorphism and RNAi sites, and summarizing known functions for most genes studied in this organism.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Caenorhabditis elegans / genetics*
  • Caenorhabditis elegans / physiology
  • Caenorhabditis elegans Proteins / chemistry*
  • Caenorhabditis elegans Proteins / genetics*
  • DNA, Complementary / chemistry
  • Databases, Genetic*
  • Expressed Sequence Tags / chemistry
  • Genome, Helminth
  • Genomics
  • Internet
  • Polymorphism, Single Nucleotide
  • RNA Interference
  • Software*
  • User-Computer Interface


  • Caenorhabditis elegans Proteins
  • DNA, Complementary