Quetiapine in the treatment of behavioral disturbances in patients with Huntington's disease

Psychosomatics. Jan-Feb 2006;47(1):70-2. doi: 10.1176/appi.psy.47.1.70.

Abstract

The effect of quetiapine (an atypical antipsychotic with minimal extrapyramidal side effects) on motor as well as behavioral symptoms was studied in five consecutive patients with Huntington's disease in a long-term facility. Improvement of behavioral symptoms (i.e., psychotic symptoms, agitation, irritability, and insomnia) without worsening of motor functioning were noted.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use*
  • Dibenzothiazepines / adverse effects
  • Dibenzothiazepines / therapeutic use*
  • Female
  • Follow-Up Studies
  • Humans
  • Huntington Disease / complications*
  • Huntington Disease / psychology
  • Long-Term Care / methods
  • Long-Term Care / psychology
  • Male
  • Mental Disorders / drug therapy*
  • Mental Disorders / etiology*
  • Mental Disorders / psychology
  • Psychomotor Agitation / drug therapy
  • Psychomotor Agitation / etiology
  • Psychomotor Agitation / psychology
  • Psychotic Disorders / drug therapy
  • Psychotic Disorders / etiology
  • Psychotic Disorders / psychology
  • Quetiapine Fumarate

Substances

  • Antipsychotic Agents
  • Dibenzothiazepines
  • Quetiapine Fumarate