Sucrose-specific induction of the anthocyanin biosynthetic pathway in Arabidopsis

Plant Physiol. 2006 Feb;140(2):637-46. doi: 10.1104/pp.105.072579. Epub 2005 Dec 29.


Sugars act as signaling molecules, whose signal transduction pathways may lead to the activation or inactivation of gene expression. Whole-genome transcript profiling reveals that the flavonoid and anthocyanin biosynthetic pathways are strongly up-regulated following sucrose (Suc) treatment. Besides mRNA accumulation, Suc affects both flavonoid and anthocyanin contents. We investigated the effects of sugars (Suc, glucose, and fructose) on genes coding for flavonoid and anthocyanin biosynthetic enzymes in Arabidopsis (Arabidopsis thaliana). The results indicate that the sugar-dependent up-regulation of the anthocyanin synthesis pathway is Suc specific. An altered induction of several anthocyanin biosynthetic genes, consistent with in vivo sugar modulation of mRNA accumulation, is observed in the phosphoglucomutase Arabidopsis mutant accumulating high levels of soluble sugars.

MeSH terms

  • Anthocyanins / biosynthesis*
  • Anthocyanins / genetics
  • Arabidopsis / anatomy & histology
  • Arabidopsis / genetics
  • Arabidopsis / metabolism*
  • Arabidopsis Proteins / genetics
  • Carbohydrate Metabolism
  • Flavonols / genetics
  • Flavonols / metabolism
  • Gene Expression Regulation, Plant
  • Mutation
  • Phosphoglucomutase / genetics
  • RNA, Messenger / metabolism
  • Signal Transduction
  • Sucrose / pharmacology*


  • Anthocyanins
  • Arabidopsis Proteins
  • Flavonols
  • RNA, Messenger
  • Sucrose
  • Phosphoglucomutase