Ehlers-Danlos syndrome: correlation with headache disorders in a young woman

J Headache Pain. 2005 Dec;6(6):474-5. doi: 10.1007/s10194-005-0256-0.


Ehlers-Danlos syndrome is a rare inherited illness, which includes an autosomal dominant and also a recessive X-linked variant. Its main clinical characteristic is a generalised connective tissue involving collagen and elastin, causing fragile and hyperextensible skin, loose jointedness and bruising. Many clinical subtypes are described, each of a different severity degree pattern. The correlation of this syndrome and headache disorders is rare. In this paper we describe the case of a young woman with Type II (less severe) Ehlers-Danlos Syndrome and headache.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / pathology
  • Calcium Channel Blockers / therapeutic use
  • Ehlers-Danlos Syndrome / complications*
  • Ehlers-Danlos Syndrome / diagnostic imaging
  • Ehlers-Danlos Syndrome / pathology
  • Female
  • Flunarizine / therapeutic use
  • Headache / complications*
  • Headache / diagnostic imaging
  • Headache / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Migraine Disorders / complications
  • Migraine Disorders / epidemiology
  • Mouth / diagnostic imaging
  • Radiography


  • Calcium Channel Blockers
  • Flunarizine