Adverse obstetric outcome in women with a history of infertility: a retrospective study

J Obstet Gynaecol. 2006 Jan;26(1):35-6. doi: 10.1080/01443610500364012.

Abstract

Women with a history of infertility are associated with a higher incidence of adverse pregnancy outcome. This retrospective study reviewed 105 women with a known history of infertility; of these 105 women, 77 (73%) conceived spontaneously and 28 (27%) had assisted conception. Our finding confirms higher perinatal complications; relative ratios (RR) for pre-eclampsia was 4.6 (95% CI=2.1-9.9), intrauterine growth restriction 4.8 (95% CI=1.9-12.0), gestational diabetes 1.8 (95% CI=0.5-5.8), pre-term premature rupture of membrane 2.3 (95% CI=0.6-8.8) and pre-term labour 2.6 (95% CI=1.1-5.9). We postulate that women with a history of infertility are at high risk of such obstetric complications and may benefit from intensified antenatal care.

MeSH terms

  • Adult
  • Female
  • Fertilization
  • Humans
  • Infertility, Female / complications*
  • Infertility, Female / therapy
  • Pregnancy
  • Pregnancy Complications / epidemiology
  • Pregnancy Complications / etiology*
  • Pregnancy Outcome / epidemiology
  • Prenatal Care
  • Reproductive Techniques, Assisted
  • Retrospective Studies
  • United Kingdom / epidemiology