Treatment of keloids and hypertrophic scars

Indian J Dermatol Venereol Leprol. Jan-Feb 2005;71(1):3-8. doi: 10.4103/0378-6323.13777.


Clinicians always find it difficult to treat hypertrophic scars and keloids. Various treatment modalities are available. Intralesional corticosteroids, topical applications, cryotherapy, surgery, laser therapy, and silicone sheeting are the widely used options. Radiation therapy can also help in cases of recalcitrant keloids. Most recently, pulsed-dye laser has been successfully used to treat keloids and hypertrophic scars. There are no set guidelines for the treatment of keloids. Treatment has to be individualized depending upon the distribution, size, thickness, and consistency of the lesions and association of inflammation. A combination approach to therapy seems to be the best option.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Administration, Topical
  • Adrenal Cortex Hormones / therapeutic use
  • Cicatrix, Hypertrophic / diagnosis*
  • Cicatrix, Hypertrophic / therapy*
  • Cryotherapy / methods
  • Female
  • Fluorouracil / therapeutic use
  • Follow-Up Studies
  • Humans
  • India
  • Injections, Intralesional
  • Keloid / diagnosis*
  • Keloid / therapy*
  • Laser Therapy / methods
  • Male
  • Risk Assessment
  • Treatment Outcome


  • Adrenal Cortex Hormones
  • Fluorouracil