Acute skin failure: concept, causes, consequences and care

Indian J Dermatol Venereol Leprol. Nov-Dec 2005;71(6):379-85. doi: 10.4103/0378-6323.18007.


Acute skin failure is a state of total dysfunction of the skin resulting from different dermatological conditions. It constitutes a dermatological emergency and requires a multi-disciplinary, intensive care approach. Its effective management is possible only when the underlying pathomechanism of each event is clear to the treating clinician. The concept of skin failure is new to non-dermatologist clinicians and sketchy among many dermatologists. Here the pathomechanism of skin failure has been analyzed and a guideline for monitoring has been provided. There is a need for intensive care units for patients with acute skin failure.

Publication types

  • Review

MeSH terms

  • Body Temperature Regulation / physiology*
  • Humans
  • Patient Care Team
  • Skin / physiopathology*
  • Skin Care
  • Skin Diseases / mortality
  • Skin Diseases / physiopathology*
  • Water Loss, Insensible / physiology
  • Water-Electrolyte Imbalance / physiopathology