Chemical biology at the crossroads of molecular structure and mechanism

Nat Chem Biol. 2005 Nov;1(6):300-3. doi: 10.1038/nchembio1105-300.

Abstract

Chemical insight into biological function is the holy grail of structural biology. Small molecules are central players as building blocks, effectors and probes of macromolecular structure and function.

Publication types

  • Review

MeSH terms

  • Biochemistry / methods*
  • Crystallography, X-Ray
  • Molecular Biology / methods*
  • Molecular Conformation
  • RNA / chemistry
  • RNA / metabolism
  • Structure-Activity Relationship

Substances

  • RNA