Aging and humoral immunity

Md Med J. 1992 Jul;41(7):609-13.

Abstract

If human antibody responses undergo molecular shifts similar to those identified in mice, the appropriate immunization strategy for the elderly would be a passive administration of the protective antibody from young donors rather than an attempt to boost the individual's own response with a more potent vaccine, because the shifted immune system can no longer make the right kind of antibody.

MeSH terms

  • Aging / immunology*
  • Animals
  • Antibody Formation*
  • Humans