Induction of germ cell formation by oskar

Nature. 1992 Jul 30;358(6385):387-92. doi: 10.1038/358387a0.


The oskar gene directs germ plasm assembly and controls the number of germ cell precursors formed at the posterior pole of the Drosophila embryo. Mislocalization of oskar RNA to the anterior pole leads to induction of germ cells at the anterior. Of the eight genes necessary for germ cell formation at the posterior, only three, oskar, vasa and tudor, are essential at an ectopic site.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Abdomen / embryology
  • Animals
  • Drosophila melanogaster / embryology*
  • Embryonic Induction
  • Gene Expression
  • Genes
  • Germ Cells*
  • Morphogenesis
  • RNA, Messenger / metabolism


  • RNA, Messenger