Abstract
Despite being a common condition in pregnancy, and despite propylthiouracil (PTU) being perceived as safer than methimazole, there are virtually no epidemiological controlled studies on malformation rate an neurobehavioral outcomes with the former. This knowledge gap must be filled to ensure fetal safety.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Abnormalities, Drug-Induced / etiology
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Antithyroid Agents / adverse effects
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Antithyroid Agents / blood*
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Antithyroid Agents / pharmacokinetics
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Drug Administration Schedule
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Drug Monitoring
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Female
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Humans
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Infant, Newborn
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Knowledge
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Maternal-Fetal Exchange
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Methimazole / adverse effects
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Methimazole / blood*
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Methimazole / pharmacokinetics
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Milk, Human / chemistry
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Pregnancy
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Propylthiouracil / adverse effects
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Propylthiouracil / blood*
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Propylthiouracil / pharmacokinetics
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Thyrotoxicosis / chemically induced
Substances
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Antithyroid Agents
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Methimazole
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Propylthiouracil