Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. Oct-Dec 2005;25(4):205-30.
doi: 10.1080/07388550500376166.

Natural and Modified (1-->3)-beta-D-glucans in Health Promotion and Disease Alleviation


Natural and Modified (1-->3)-beta-D-glucans in Health Promotion and Disease Alleviation

Djordje B Zeković et al. Crit Rev Biotechnol. .


A number of polysaccharides with beta-glycosidic linkage are widespread in nature in a variety of sources. All have a common structure and the (1-->3)-beta-D-glucan backbone is essential. They have attracted attention over the years because of their bioactive and medicinal properties. In many cases their functional role is a mystery, in others it is well established. Because of their insoluble chemical nature, particulate (1-->3)-beta-D-glucans are not suitable for many medical applications. Various methods of changing or modifying the beta-D-glucan chemical structure and transforming it to a soluble form have been published. The beta-D-glucan bioactive properties can be affected positively or negatively by such modifications. This review examines beta-glucan sources in nature, health effects and structure-activity relationships. It presents the current state of beta-D-glucan solubilization methods and discusses their effectiveness and application possibilities for the future.

Similar articles

See all similar articles

Cited by 28 articles

See all "Cited by" articles

Publication types

MeSH terms

LinkOut - more resources