International Consensus Statement on an Update of the Classification Criteria for Definite Antiphospholipid Syndrome (APS)

J Thromb Haemost. 2006 Feb;4(2):295-306. doi: 10.1111/j.1538-7836.2006.01753.x.

Abstract

New clinical, laboratory and experimental insights, since the 1999 publication of the Sapporo preliminary classification criteria for antiphospholipid syndrome (APS), had been addressed at a workshop in Sydney, Australia, before the Eleventh International Congress on antiphospholipid antibodies. In this document, we appraise the existing evidence on clinical and laboratory features of APS addressed during the forum. Based on this, we propose amendments to the Sapporo criteria. We also provide definitions on features of APS that were not included in the updated criteria.

Publication types

  • Consensus Development Conference
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Antiphospholipid / blood
  • Antiphospholipid Syndrome / classification*
  • Antiphospholipid Syndrome / complications
  • Antiphospholipid Syndrome / diagnosis
  • Antiphospholipid Syndrome / immunology
  • Female
  • Heart Diseases / etiology
  • Humans
  • Kidney Diseases / etiology
  • Nervous System Diseases / etiology
  • Pregnancy
  • Pregnancy Complications / classification
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / immunology
  • Prognosis
  • Risk Factors
  • Skin Diseases / etiology
  • Thrombocytopenia / etiology

Substances

  • Antibodies, Antiphospholipid