Changes in amplitude-integrated electroencephalography in neonates treated with extracorporeal membrane oxygenation: a pilot study

J Pediatr. 2006 Jan;148(1):125-7. doi: 10.1016/j.jpeds.2005.07.044.

Abstract

Neonates (n = 20) treated with extracorporeal membrane oxygenation were evaluated with serial amplitude-integrated electroencephalography (aEEG). There was no acute change in aEEG during extracorporeal membrane oxygenation cannulation, nor were there lateralizing effects. An abnormal aEEG predicted death or moderate to severe intracranial neuropathology with sensitivity = 1.0, specificity = 0.75, positive predictive value = 0.86, and negative predictive value = 1.0.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Infarction / diagnosis
  • Brain Infarction / physiopathology
  • Brain Injuries / diagnosis*
  • Brain Injuries / physiopathology
  • Electroencephalography / methods*
  • Extracorporeal Membrane Oxygenation / adverse effects
  • Extracorporeal Membrane Oxygenation / methods*
  • Female
  • Humans
  • Hydrocephalus / diagnosis
  • Hydrocephalus / physiopathology
  • Infant, Newborn
  • Intensive Care Units, Neonatal
  • Intracranial Hemorrhages / diagnosis
  • Intracranial Hemorrhages / physiopathology
  • Magnetic Resonance Imaging
  • Male
  • Pilot Projects
  • Respiratory Insufficiency / therapy*
  • Sensitivity and Specificity