Effect of micronutrient supplement on health and nutritional status of schoolchildren: mental function

Nutrition. 2006 Jan;22(1 Suppl):S26-32. doi: 10.1016/j.nut.2004.07.021.


Objective: We evaluated the effect of a micronutrient-fortified beverage on mental function in schoolchildren.

Methods: This double-blind, placebo-controlled, matched-pair, cluster, randomized feeding trial assessed baseline before supplementation and after 14 mo in a cohort of 608 children aged 6 to 15 y who received a micronutrient-fortified beverage or placebo. Children in two classes (clusters) in each of nine grades were assessed for intelligence, attention and concentration, memory, and school achievement.

Results: Mean intelligence quotient scores of the micronutrient-fortified beverage group and the placebo group at baseline and final follow-up were not significantly different. Mean verbal and performance scores and increments were also not different. After supplementation, attention-concentration increment scores of the micronutrient group were significantly higher (P < 0.05) than those of the placebo group. Mean and incremental scores of the supplemented group on the memory scale were not significantly different from those of the placebo group.

Conclusions: Supplementation with a beverage fortified with a range of micronutrients significantly improved attention-concentration over 14 mo, but not intelligence quotient, memory, or school achievement among middle-income schoolchildren.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Attention / drug effects*
  • Child
  • Cluster Analysis
  • Cognition / drug effects*
  • Double-Blind Method
  • Female
  • Food, Fortified
  • Health Status*
  • Humans
  • India
  • Intelligence / drug effects
  • Male
  • Mental Recall / drug effects
  • Micronutrients / administration & dosage
  • Micronutrients / pharmacology*
  • Nutritional Status*
  • Schools
  • Treatment Outcome


  • Micronutrients