The Role of the Rcs Phosphorelay in Enterobacteriaceae

Res Microbiol. 2006 Apr;157(3):206-12. doi: 10.1016/j.resmic.2005.11.005. Epub 2006 Jan 4.

Abstract

The Rcs phosphorelay is composed of the sensor kinase, RcsC, the HPt-domain protein RcsD and the response regulator, RcsB. In this review we discuss the role of the Rcs phosphorelay in the Enterobacteriaceae, highlighting the observation that the Rcs phosphorelay appears to play a key role in the temporal regulation of biofilm formation and pathogenicity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Adhesion
  • Bacterial Proteins / metabolism*
  • Biofilms*
  • Enterobacteriaceae / metabolism*
  • Enterobacteriaceae / pathogenicity
  • Escherichia coli / physiology
  • Escherichia coli Proteins / metabolism*
  • Multienzyme Complexes / metabolism*
  • Phosphoprotein Phosphatases / metabolism*
  • Phosphotransferases / metabolism*
  • Protein Kinases / metabolism*
  • Salmonella / pathogenicity
  • Salmonella / physiology
  • Signal Transduction
  • Virulence Factors / genetics
  • Virulence Factors / physiology
  • Yersinia / physiology

Substances

  • Bacterial Proteins
  • Escherichia coli Proteins
  • Multienzyme Complexes
  • Virulence Factors
  • RcsB protein, Bacteria
  • Phosphotransferases
  • Protein Kinases
  • rcsD protein, E coli
  • Phosphoprotein Phosphatases