A short review of the pathogenesis of Sjögren's syndrome

Autoimmun Rev. 2006 Feb;5(2):132-5. doi: 10.1016/j.autrev.2005.08.005. Epub 2005 Sep 28.


Sjögren's syndrome can present in a heterogeneous manner with symptoms varying from systemic features such as unexplained fever, weight loss and neurological manifestations to the more typical symptoms of dry mucus membranes. There is discussion of the wide differential diagnosis, followed by a brief overview of the diagnosis, extraglandular manifestations and pathogenesis of primary Sjögren's syndrome.

Publication types

  • Review

MeSH terms

  • Adult
  • Bronchiectasis / pathology
  • Diagnosis, Differential
  • Female
  • Humans
  • Pleural Effusion / pathology
  • Sjogren's Syndrome / diagnosis*
  • Sjogren's Syndrome / etiology
  • Synovitis / pathology