Gynecomastia in patients with prostate cancer: update on treatment options

Prostate Cancer Prostatic Dis. 2006;9(2):109-14. doi: 10.1038/sj.pcan.4500859. Epub 2006 Jan 24.

Abstract

Non-steroidal antiandrogen monotherapy offers potential quality of life benefits over other treatment modalities in patients with prostate cancer. Nevertheless, gynecomastia and breast pain still represent the most bothersome side effects during this treatment. In this update article, recent advances in the management options for gynecomastia/breast pain caused by hormonal manipulation are reviewed and critically analyzed.

Publication types

  • Review

MeSH terms

  • Aged
  • Androgen Antagonists / therapeutic use*
  • Antineoplastic Agents, Hormonal / therapeutic use
  • Comorbidity
  • Follow-Up Studies
  • Gynecomastia / diagnosis
  • Gynecomastia / epidemiology*
  • Gynecomastia / therapy*
  • Humans
  • Male
  • Mastectomy / methods
  • Middle Aged
  • Prostatic Neoplasms / diagnosis*
  • Prostatic Neoplasms / epidemiology*
  • Prostatic Neoplasms / therapy
  • Radiotherapy, Adjuvant
  • Risk Assessment
  • Severity of Illness Index
  • Tamoxifen / therapeutic use*
  • Treatment Outcome

Substances

  • Androgen Antagonists
  • Antineoplastic Agents, Hormonal
  • Tamoxifen