Sexual pleasure in women with obsessive-compulsive disorder?

J Affect Disord. 2006 Mar;91(1):19-25. doi: 10.1016/j.jad.2005.12.006. Epub 2006 Jan 24.

Abstract

Background: Although patients with OCD have reported sexual dissatisfaction frequently, controlled studies are sparse. This study compared subjective appreciation of sexuality and sexual functioning between OCD patients and healthy subjects and controlled for the influence of medication or OCD subtypes on sexual functioning and satisfaction.

Methods: Self-report questionnaires were sent to 350 female outpatients with OCD and 101 questionnaires were completed.

Results: OCD patients reported significantly more sexual disgust (t = 4.48, p < 0.001), less sexual desire (t = 5.52, p < 0.001), sexual arousal (t = 4.28, p < 0.001), and satisfying orgasms (t = 4.94, p < 0.001), than controls. Neither medication nor OCD phenotypes did affect outcome.

Limitations: A self-report questionnaire and relatively low response-rate (29%) could have biased the results and the sample was limited to women so results might not be generalisable to men.

Conclusions: Female patients with OCD report low sexual pleasure, high sexual disgust and diminished sexual functioning, which are not only attributed to medication or contamination obsessions. In the future, clinicians should explicitly ask for sexual function in the assessment of patients with OCD.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use
  • Clomipramine / adverse effects
  • Clomipramine / therapeutic use
  • Coitus
  • Drive
  • Female
  • Humans
  • Middle Aged
  • Obsessive-Compulsive Disorder / diagnosis*
  • Obsessive-Compulsive Disorder / drug therapy
  • Obsessive-Compulsive Disorder / psychology
  • Personal Satisfaction*
  • Selective Serotonin Reuptake Inhibitors / adverse effects
  • Selective Serotonin Reuptake Inhibitors / therapeutic use
  • Sexual Dysfunctions, Psychological / diagnosis*
  • Sexual Dysfunctions, Psychological / psychology
  • Surveys and Questionnaires

Substances

  • Antipsychotic Agents
  • Serotonin Uptake Inhibitors
  • Clomipramine