Case report: localization of occult insulinoma by intra-arterial stimulation with calcium and venous sampling technique

Clin Radiol. 1992 Jul;46(1):55-6. doi: 10.1016/s0009-9260(05)80036-4.


Hypoglycaemia as a result of insulin secreting tumours can be treated effectively by surgery. However pre-operative localization is desirable as the majority of these tumours are small and in 20% of the cases may be multiple. We describe a 1 cm insulinoma being localized pre-operatively by selective arterial stimulation with calcium and venous sampling for insulin. This technique is sensitive and relatively non-invasive. We believe that it is potentially very valuable in pre-operative localization of occult insulinomas.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Calcium*
  • Humans
  • Insulin / blood
  • Insulinoma / blood
  • Insulinoma / diagnosis*
  • Male
  • Pancreatic Neoplasms / blood
  • Pancreatic Neoplasms / diagnosis*
  • Preoperative Care
  • Stimulation, Chemical


  • Insulin
  • Calcium