Planarian regeneration: its end is its beginning

Cell. 2006 Jan 27;124(2):241-5. doi: 10.1016/j.cell.2006.01.012.


Why does regeneration take place in some animals but not others? Increased understanding of gene function is required to dissect the genetics, cell biology, and physiological aspects that make regeneration possible. An unlikely model animal, the planarian Schmidtea mediterranea, is proving valuable in this endeavor.

Publication types

  • Review

MeSH terms

  • Animals
  • Models, Animal
  • Planarians / genetics*
  • Planarians / physiology*
  • RNA Interference
  • Regeneration / physiology*
  • Stem Cells / physiology