Prenatal detection of birth defects in a Malaysian population: estimation of the influence of termination of pregnancy on birth prevalence in a developing country

Aust N Z J Obstet Gynaecol. 2006 Feb;46(1):55-7. doi: 10.1111/j.1479-828X.2006.00516.x.


We studied 253 women with a pregnancy complicated by a birth defect and 506 controls to determine the frequency and type of prenatal tests and the types of defects detected antenatally. Most women had at least one ultrasound examination, but the frequency of other screening tests was low. Only 38 (15%) of defects were detected antenatally (37 by ultrasound). Birth prevalence is unlikely to be affected by pregnancy termination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abortion, Induced*
  • Adult
  • Case-Control Studies
  • Congenital Abnormalities / diagnosis*
  • Congenital Abnormalities / epidemiology*
  • Congenital Abnormalities / prevention & control
  • Down Syndrome / diagnosis
  • Down Syndrome / epidemiology
  • Female
  • Humans
  • Infant, Newborn
  • Malaysia / epidemiology
  • Male
  • Neural Tube Defects / diagnosis
  • Neural Tube Defects / epidemiology
  • Pregnancy
  • Prenatal Diagnosis*
  • Prevalence
  • Ultrasonography, Prenatal