Background: Although cardiovascular disease is the leading cause of mortality in diabetic patients, little is known about the impact of glycemic control on ventricular tachycardia (VT).
Objective: To investigate whether hemoglobin A1c (HbA1c) is associated with increased incidence of VT.
Methods: A retrospective study of 336 implantable cardioverter-defibrillator patients (both diabetes mellitus (DM) and non-DM) was conducted.
Results: HbA1c levels between 8% and 10% had a significant association with spontaneous VT, but not with QT/QTc.
Conclusions: Glycemic index is a significant predictor of spontaneous VT, independently of QT interval. Optimal glycemic control may help reduce occurrence of VT and sudden cardiac death in high-risk DM patients.