Evaluation of the immunochromatographic CORIS Giardia-Strip test for rapid diagnosis of Giardia lamblia

Eur J Clin Microbiol Infect Dis. 2006 Feb;25(2):112-5. doi: 10.1007/s10096-006-0088-0.


The aim of this study was to evaluate the performance of the CORIS Giardia-Strip test (CORIS Bioconcept, Gembloux, Belgium) as a rapid initial method for the routine diagnosis of giardiasis. Compared to a commercial ELISA-coproantigen test (ProSpect Giardia-ELISA-microplate assay; Remel, Lenexa, KS, USA), the commercial strip test had a sensitivity of 58%, a specificity of 99%, a positive predictive value of 93% and a negative predictive value of 93% (n=158). These results are comparable to those obtained using microscopy of direct wet-mounted stool. Since the CORIS Giardia-Strip test is simpler to perform, it can replace direct wet-mounted stool microscopy for the rapid diagnosis of giardiasis; however, its sensitivity is inferior to that of other immunochromatographic antigen detection tests and fresh stool samples are required for its use. Nevertheless, the results suggest that a positive CORIS Giardia-Strip test outcome does not need confirmation, while samples with negative results should be re-examined using another, more sensitive, test.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antigens, Protozoan / immunology
  • Enzyme-Linked Immunosorbent Assay
  • Feces / parasitology
  • Giardia lamblia / immunology
  • Giardia lamblia / isolation & purification*
  • Giardiasis / diagnosis*
  • Giardiasis / microbiology*
  • Humans
  • Microscopy
  • Predictive Value of Tests
  • Reagent Strips*
  • Sensitivity and Specificity


  • Antigens, Protozoan
  • Reagent Strips