Abstract
A physician orders fosphenytoin to be administered intramuscularly in a dosage of 30 mL in volume. A change in the traditional practice of limiting intramuscular injection volumes to 5 mL in adult patients is discussed.
MeSH terms
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Anticonvulsants / administration & dosage*
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Anticonvulsants / adverse effects
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Dose-Response Relationship, Drug
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Humans
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Injections, Intramuscular / adverse effects
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Injections, Intramuscular / methods
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Injections, Intramuscular / nursing
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Phenytoin / administration & dosage
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Phenytoin / adverse effects
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Phenytoin / analogs & derivatives*
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Prodrugs / administration & dosage*
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Prodrugs / adverse effects
Substances
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Anticonvulsants
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Prodrugs
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Phenytoin
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fosphenytoin