Impulse oscillometry is sensitive to bronchoconstriction after eucapnic voluntary hyperventilation or exercise

J Asthma. 2006 Jan-Feb;43(1):49-55. doi: 10.1080/02770900500448555.

Abstract

Airway responses were compared following 6-minute eucapnic voluntary hyperventilation and 6-minute exercise challenges by examining resting and post-challenge impulse oscillometry and spirometry variables. Twenty-two physically active individuals with probable exercise-induced bronchoconstriction took part in this study. Impulse oscillometry and spirometry were performed at baseline and for 20 minutes post-challenge at 5-minute intervals. High correlation was found between the two measures of change in airway function for both methods of challenge. Impulse oscillometry detected a difference in degree of response to the challenges, whereas spirometry indicated no difference, suggesting that impulse oscillometry is a more sensitive measure of change in airway function.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Airway Resistance / physiology
  • Area Under Curve
  • Asthma, Exercise-Induced / physiopathology*
  • Bronchoconstriction / physiology*
  • Exercise / physiology*
  • Female
  • Forced Expiratory Volume / physiology
  • Humans
  • Hyperventilation / chemically induced
  • Hyperventilation / physiopathology*
  • Male
  • Maximal Midexpiratory Flow Rate / physiology
  • Oscillometry
  • Pulmonary Ventilation / physiology*
  • Spirometry
  • Vital Capacity / physiology