Organization and variability of the maize genome

Curr Opin Plant Biol. 2006 Apr;9(2):157-63. doi: 10.1016/j.pbi.2006.01.009. Epub 2006 Feb 3.

Abstract

With a size approximating that of the human genome, the maize genome is about to become the largest plant genome yet sequenced. Contributing to that size are a whole-genome duplication event and a retrotransposition explosion that produced a large amount of repetitive DNA. This DNA is greatly under-represented in cDNA collections, so analysis of the maize transcriptome has been an expedient way of assessing the gene content of maize. Over 2 million maize cDNA sequences are now available, making maize the third most widely studied organism, behind mouse and man. To date, the sequencing of large-sized DNA clones has been largely driven by the genetic interests of different investigators. The recent construction of a physical map that is anchored to the genetic map will aid immensely in the maize genome-sequencing effort. However, studies showing that the repetitive DNA component is highly polymorphic among maize inbred lines point to the need to sample vertically a few specific regions of the genome to evaluate the extent and importance of this variability.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Chromosome Mapping*
  • DNA, Plant
  • Gene Library
  • Genome, Plant*
  • Polymorphism, Genetic*
  • Sequence Analysis, DNA
  • Species Specificity
  • Zea mays / genetics*

Substances

  • DNA, Plant