The striatin family: a new signaling platform in dendritic spines

J Physiol Paris. 2006 Mar-May;99(2-3):146-53. doi: 10.1016/j.jphysparis.2005.12.006. Epub 2006 Feb 7.


Proteins of the striatin family have been identified in all multicellular animals. They are multidomain molecules containing several protein-interacting motifs. In mammals, these proteins are principally expressed in neurons with a somato-dendritic localization and high concentration in dendritic spines. Recent reports suggest that the proteins of the striatin family are molecular scaffolds that act as links between signal transduction and vesicular trafficking.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Calmodulin-Binding Proteins / chemistry
  • Calmodulin-Binding Proteins / classification*
  • Calmodulin-Binding Proteins / physiology*
  • Dendritic Spines / metabolism*
  • Humans
  • Models, Biological
  • Molecular Structure
  • Protein Structure, Tertiary / physiology
  • Signal Transduction / physiology*


  • Calmodulin-Binding Proteins