The effect of interaction between hepatitis C virus and cigarette smoking on the risk of hepatocellular carcinoma

Br J Cancer. 2006 Mar 13;94(5):737-9. doi: 10.1038/sj.bjc.6602981.

Abstract

We evaluated the interaction between hepatitis C virus (HCV) and cigarette smoking on death from hepatocellular cancer in The Japan Collaborative Cohort Study. The odds ratio of death from HCC for smoking was 9.60 (1.50-61.35) and 1.71(0.58-5.08) among anti-HCV positive and negative individuals, respectively.

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Hepatocellular / epidemiology
  • Carcinoma, Hepatocellular / mortality*
  • Carcinoma, Hepatocellular / virology
  • Cohort Studies
  • Female
  • Hepatitis C / complications*
  • Humans
  • Japan / epidemiology
  • Liver Neoplasms / epidemiology
  • Liver Neoplasms / mortality*
  • Liver Neoplasms / virology
  • Male
  • Middle Aged
  • Odds Ratio
  • Risk Factors
  • Smoking / adverse effects*