[Studies on the chemical constituents in root of Coleus forskohlii]

Zhongguo Zhong Yao Za Zhi. 2005 Nov;30(22):1753-5.
[Article in Chinese]

Abstract

Objective: To study the chemical constituents in root of Coleusforskohlii.

Method: The chemical constituents were isolated by column chromatography. The structures were elucidated on the basis of IR, MS, 1H-NMR, 13C-NMR and 2D-NMR experiments.

Result: Six compounds were obtained and the structures were identified as 14-deoxycoleon U (1), demethylcryptojaponol (2), alpha-amyrin (3), betulic acid (4), alpha-cedrol (5) and beta-sitosterol (6).

Conclusion: Compounds 1 and 2 were isolated from the genus Coleus for the first time. Compounds 3 and 4 were isolated from C. forskohlii for the first time.

MeSH terms

  • Coleus / chemistry*
  • Diterpenes / chemistry
  • Diterpenes / isolation & purification*
  • Oleanolic Acid / analogs & derivatives*
  • Oleanolic Acid / chemistry
  • Oleanolic Acid / isolation & purification
  • Plant Roots / chemistry
  • Plants, Medicinal / chemistry*
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*

Substances

  • 14-deoxycoleon U
  • Diterpenes
  • Triterpenes
  • betulinic acid
  • Oleanolic Acid
  • beta-amyrin