Microalbuminuria prevalence study (MAPS) in hypertensive patients with type 2 diabetes in Thailand

J Med Assoc Thai. 2005 Nov;88(11):1624-9.

Abstract

Background: Microalbuminuria represents the earliest clinical evidence of diabetic nephropathy, and is a marker of increased cardiovascular (CV) morbidity and mortality.

Objectives: This analysis of Thai data from the Microalbuminuria Prevalence Study (MAPS) assessed the prevalence of macroalbuminuria and microalbuminuria in hypertensive patients with type 2 diabetes.

Design: Cross-sectional clinic-based epidemiological study.

Material and method: A total of 100 patients were enrolled, of which 97 patients constituted the per-protocol population (patients with bacteriuria and haematuria were excluded). Patients attended one study visit with no follow-up.

Results: Overall, the prevalence of diabetic kidney disease was high, with macroalbuminuria contributing 13.4% [9.9-16.9; 95% confidence interval (CI)] and microalbuminuria contributing 43.3% [38.3-48.3; 95%CI].

Conclusion: Annual screening for microalbuminuria is recommended for all patients with type 2 diabetes, as early treatment is critical for reducing CV risks. Clinical studies have shown that renin-angiotensin system inhibitors can slow the progression of diabetic nephropathy.

MeSH terms

  • Albuminuria / diagnosis*
  • Albuminuria / epidemiology
  • Albuminuria / urine
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / urine*
  • Diabetic Nephropathies / diagnosis
  • Diabetic Nephropathies / epidemiology
  • Diabetic Nephropathies / urine*
  • Disease Progression
  • Female
  • Humans
  • Hypertension / complications
  • Hypertension / urine*
  • Male
  • Middle Aged
  • Prevalence
  • Renin-Angiotensin System
  • Thailand / epidemiology
  • Time Factors