Current evidence for a genetic modulation of the response to analgesics

Pain. 2006 Mar;121(1-2):1-5. doi: 10.1016/j.pain.2006.01.010. Epub 2006 Feb 10.

Authors

Jörn Lötsch¹, Gerd Geisslinger

Affiliation

¹ pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Johann Wolfgang Goethe-University, Theodor Stern Kai 7, D-60590 Frankfurt, Germany. j.loetsch@em.uni-frankfurt.de

PMID: 16472919
DOI: 10.1016/j.pain.2006.01.010

No abstract available

Publication types

Review

MeSH terms

ATP Binding Cassette Transporter, Subfamily B, Member 1 / genetics
Analgesics / therapeutic use*
Animals
Catechol O-Methyltransferase / genetics
Cytochrome P-450 CYP2D6 / genetics
Humans
Pain / drug therapy*
Pain / genetics*
Pharmacogenetics*
Polymorphism, Genetic / genetics
Receptor, Melanocortin, Type 1 / genetics
Receptors, Opioid, mu / genetics

Substances

ATP Binding Cassette Transporter, Subfamily B, Member 1
Analgesics
Receptor, Melanocortin, Type 1
Receptors, Opioid, mu
Cytochrome P-450 CYP2D6
Catechol O-Methyltransferase