Genotyping of Chlamydia trachomatis from clinical specimens in Taiwan

J Med Microbiol. 2006 Mar;55(Pt 3):301-308. doi: 10.1099/jmm.0.46262-0.

Abstract

This study was conducted to determine the prevalence and distribution of Chlamydia trachomatis genotypes in Taiwan. Urine and endocervical-swab samples were collected from two hospitals located in northern and southern Taiwan. The genotypes of a total of 145 samples positive for C. trachomatis were analysed by sequencing the omp1 gene and this was successful in 102 samples. Nine different C. trachomatis genotypes were identified. Genotype E was the most prevalent (22 %), followed by D and Da (19 %), F (16 %), J (15 %), K (11 %), G (11 %), H (6 %) and Ba (2 %). There was a geographical difference in the prevalence of genotype H (P < 0.018) between northern and southern Taiwan. Sequence mutation analysis by blast searching against GenBank reference sequences identified 12 genetic variants from a total of 102 omp1 gene sequences.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Cervix Uteri / microbiology
  • Chlamydia Infections / epidemiology*
  • Chlamydia Infections / microbiology
  • Chlamydia trachomatis / classification*
  • Chlamydia trachomatis / genetics
  • Chlamydia trachomatis / isolation & purification
  • Female
  • Female Urogenital Diseases / epidemiology*
  • Female Urogenital Diseases / microbiology
  • Genotype
  • Humans
  • Molecular Sequence Data
  • Porins / genetics
  • Prevalence
  • Sequence Analysis, DNA
  • Taiwan / epidemiology
  • Urine / microbiology

Substances

  • Porins
  • omp1 protein, Chlamydia trachomatis

Associated data

  • GENBANK/DQ155295
  • GENBANK/DQ155296
  • GENBANK/DQ155297
  • GENBANK/DQ155298
  • GENBANK/DQ155299
  • GENBANK/DQ155300
  • GENBANK/DQ287919
  • GENBANK/DQ287920
  • GENBANK/DQ287921