Immunity to transmissible (coronaviral) enteritis of turkeys (bluecomb)

Am J Vet Res. 1975 Apr;36(4 Pt 2):553-5.


Turkey flocks recovering from natural and laboratory induced coronaviral enteritis developed lifelong immunity. Virus neutralization tests indicated that neutralization capacity of serums from recovered turkeys was low. One-way cross challenge test using turkeys inoculated with various bluecomb isolates revealed close antigenic relationship or antigenic identity among bluecomb isolates. The controlled application of intestinal preparations containing coronavirus as a vaccination procedure had value in developing active lasting immunity but it has limitations in areas that are attempting to eliminate the disease by a depopulation program. Killed vaccines injected parenterally did not produce a detectable immunity.

MeSH terms

  • Animals
  • Coronaviridae / growth & development
  • Coronaviridae / immunology
  • Coronavirus, Turkey*
  • Embryo, Nonmammalian
  • Enteritis / immunology
  • Enteritis / pathology
  • Enteritis / veterinary*
  • Fluorescent Antibody Technique
  • Intestines / pathology
  • Neutralization Tests
  • Poultry Diseases / immunology*
  • Poultry Diseases / pathology
  • Reoviridae Infections / immunology
  • Reoviridae Infections / pathology
  • Reoviridae Infections / veterinary*
  • Reoviridae*
  • Turkeys*