Despite high satisfaction, majority of gastro-oesophageal reflux disease patients continue to use proton pump inhibitors after antireflux surgery

Aliment Pharmacol Ther. 2006 Mar 1;23(5):601-5. doi: 10.1111/j.1365-2036.2006.02788.x.

Abstract

Background: While antireflux surgery is effective in controlling symptoms of gastro-oesophageal reflux, its role in eliminating the use of antireflux medicines after surgery and as such its long-term cost-effectiveness remains controversial.

Aim: To assess the patient satisfaction and the continued medication use following laparoscopic Nissen fundoplication at a tertiary level community hospital.

Methods: Adult patients who underwent laparoscopic Nissen fundoplication at our institution over a period of over 3 years were asked to complete a questionnaire recording their demographic information, date and reason for the surgery, preprocedure and postprocedure symptoms, smoking and alcohol use, and medication use preoperatively and post-operatively. Patients were also asked about their satisfaction with surgery.

Results: One hundred patients participated in the study. Overall, 90% patients experienced satisfaction with their surgery. Eighty percentage patients were willing to undergo surgery again, if needed. Over two-thirds (67%) patients had decrease in the severity of their symptoms. None of the patients had worsening of symptoms post-operatively. However, 80% patients were still taking antireflux medications including proton pump inhibitors (53%).

Conclusions: Most patients continue to use antireflux medications including after laparoscopic Nissen fundoplication despite high satisfaction with surgery.

MeSH terms

  • Antacids / therapeutic use
  • Cost of Illness
  • Female
  • Gastroesophageal Reflux / drug therapy
  • Gastroesophageal Reflux / economics
  • Gastroesophageal Reflux / surgery*
  • Histamine H2 Antagonists / therapeutic use
  • Humans
  • Laparoscopy / methods
  • Male
  • Mental Disorders / complications
  • Middle Aged
  • Pain / etiology
  • Patient Satisfaction*
  • Proton Pump Inhibitors
  • Treatment Outcome

Substances

  • Antacids
  • Histamine H2 Antagonists
  • Proton Pump Inhibitors